منابع مشابه
Detergent-phospholipid mixed micelles with a crystalline phospholipid core.
An unusual micelle was discovered in mixtures of the nonionic detergent octaethyleneglycol-mono-n-dodecylether with disaturated phospholipids such as 1,2-dimyristoyl-sn-glycero-3-phosphocholine or 1,2-dipalmitoyl-sn-glycero-3-phosphocholine in water. These mixtures undergo a structural transition upon cooling through the chain-melting temperatures of the respective phospholipids, resulting in t...
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Antiphospholipid syndrome (APS) is a systemic autoimmune disease with the appearance of anti-phospholipid antibody (ACLA), Anti β2GPI and lupus anticoagulant (LAC) in serum. The antigen-antibody reaction on cell surface leads to thrombosis, miscarriage and inflammation. Clinical findings are diverse and include thrombosis in veins and arteries, pregnancy loss, thrombocytopenia, neurological and...
متن کاملA cytochrome c-phospholipid complex.
Lipids may play an important role in the maintenance of proper spatial configuration between the various members of the mitochondrial electron transport chain (1, 2). Greenlees and Wainio (3) and Hatefi (4) have shown that phospholipids are essential for the activity of cytochrome c oxidase. In its present state of purity, thii enzyme contains approximately 15% phospholipid and may exist as a l...
متن کاملOpsin Is a Phospholipid Flippase
Polar lipids must flip-flop rapidly across biological membranes to sustain cellular life [1, 2], but flipping is energetically costly [3] and its intrinsic rate is low. To overcome this problem, cells have membrane proteins that function as lipid transporters (flippases) to accelerate flipping to a physiologically relevant rate. Flippases that operate at the plasma membrane of eukaryotes, coupl...
متن کاملA hybrid algorithm for the path center problem
Let a graph G = (V;E) be given. In the path center problem we want to find a path P in G such that the maximum weighted distance of P to every vertex in V is minimized. In this paper a genetic algorithm and ahybrid of genetic and ant colony algorithms are presented for the path center problem. Some test problems are examined to compare the algorithms. The results show that for almost all exampl...
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2014
ISSN: 1552-4450,1552-4469
DOI: 10.1038/nchembio.1537